Complement Factor H Binds to Denatured Rather than to Native Pentameric C-reactive Protein

Binding of the complement regulatory protein, factor H, to C-reactive protein has been reported and implicated as the biological basis for association of the H402 polymorphic variant of factor H with macular degeneration. Published studies utilize solid-phase or fluid-phase binding assays to show th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hakobyan, Svetlana, Harris, Claire L., van den Berg, Carmen W., Fernandez-Alonso, Maria Carmen, de Jorge, Elena Goicoechea, de Cordoba, Santiago Rodriguez, Rivas, German, Mangione, Palma, Pepys, Mark B., Morgan, B. Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662140/
https://ncbi.nlm.nih.gov/pubmed/18786923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803648200
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