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Total Synthesis of (+)-Lepadin F
[Image: see text] An enantioselective total synthesis of (+)-lepadin F is described. The synthetic sequence features an intermolecular aza-[3 + 3] annulation, homologation of a vinylogous amide via Eschenmoser’s episulfide contraction, and a highly stereoselective hydrogenation essential for achievi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662136/ https://ncbi.nlm.nih.gov/pubmed/18821767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802068q |
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