High Affinity Interaction between a Bivalve C-type Lectin and a Biantennary Complex-type N-Glycan Revealed by Crystallography and Microcalorimetry

Codakine is an abundant 14-kDa mannose-binding C-type lectin isolated from the gills of the sea bivalve Codakia orbicularis. Binding studies using inhibition of hemagglutination indicated specificity for mannose and fucose monosaccharides. Further experiments using a glycan array demonstrated, howev...

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Main Authors: Gourdine, Jean-Philippe, Cioci, Gianluca, Miguet, Laurence, Unverzagt, Carlo, Silva, Daniel Varón, Varrot, Annabelle, Gautier, Catherine, Smith-Ravin, Emilie Juliette, Imberty, Anne
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662075/
https://ncbi.nlm.nih.gov/pubmed/18687680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804353200
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