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The crystal structure of modified bovine fibrinogen

Here we report the crystal structure at ≈4-Å resolution of a selectively proteolyzed bovine fibrinogen. This key component in hemostasis is an elongated 340-kDa glycoprotein in the plasma that upon activation by thrombin self-assembles to form the fibrin clot. The crystals are unusual because they a...

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Detalhes bibliográficos
Main Authors: Brown, Jerry H., Volkmann, Niels, Jun, Gyo, Henschen-Edman, Agnes H., Cohen, Carolyn
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26620/
https://ncbi.nlm.nih.gov/pubmed/10618375
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