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The crystal structure of modified bovine fibrinogen

Here we report the crystal structure at ≈4-Å resolution of a selectively proteolyzed bovine fibrinogen. This key component in hemostasis is an elongated 340-kDa glycoprotein in the plasma that upon activation by thrombin self-assembles to form the fibrin clot. The crystals are unusual because they a...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Brown, Jerry H., Volkmann, Niels, Jun, Gyo, Henschen-Edman, Agnes H., Cohen, Carolyn
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.1.85
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