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2′-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena
Small RNAs ∼20–30 nucleotides (nt) in length regulate gene expression at the transcriptional and post-transcriptional levels. In the plant Arabidopsis, all small RNAs are 3′-terminal 2′-O-methylated by HEN1, whereas only a subset of small RNAs carry this modification in metazoans. This methylation i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661841/ https://ncbi.nlm.nih.gov/pubmed/19240163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1455509 |
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