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Hippocampal Erk mechanisms linking prediction error to fear extinction: Roles of shock expectancy and contextual aversive valence

Extinction of fear requires learning that anticipated aversive events no longer occur. Animal models reveal that sustained phosphorylation of the extracellular signal-regulated kinase (Erk) in hippocampal CA1 neurons plays an important role in this process. However, the key signals triggering and re...

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Bibliographische Detailangaben
Hauptverfasser: Huh, Kyu Hwan, Guzman, Yomayra F., Tronson, Natalie C., Guedea, Anita L., Gao, Can, Radulovic, Jelena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661753/
https://ncbi.nlm.nih.gov/pubmed/19318469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.1240109
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