Functional ENTPD1 Polymorphisms in African Americans With Diabetes and End-Stage Renal Disease

OBJECTIVE: The vascular ectonucleotidase ENTPD1 protects against renal injury and modulates glucose homeostasis in mouse models. We sought to determine whether human variation in ENTPD1 influences predisposition to diabetes or diabetic nephropathy. RESEARCH DESIGN AND METHODS: We analyzed ENTPD1 sin...

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Detalhes bibliográficos
Main Authors: Friedman, David J., Talbert, Matthew E., Bowden, Donald W., Freedman, Barry I., Mukanya, Yves, Enjyoji, Keiichi, Robson, Simon C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661602/
https://ncbi.nlm.nih.gov/pubmed/19095759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1214
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