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Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data

OBJECTIVE: Adiponectin (APM1, ACDC) is an adipocyte-derived protein with downregulated expression in obesity and insulin-resistant states. Several potentially regulatory single nucleotide polymorphisms (SNPs) within the APM1 gene promoter region have been associated with circulating adiponectin leve...

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Hlavní autoři: Laumen, Helmut, Saningong, Akuma D., Heid, Iris M., Hess, Jochen, Herder, Christian, Claussnitzer, Melina, Baumert, Jens, Lamina, Claudia, Rathmann, Wolfgang, Sedlmeier, Eva-Maria, Klopp, Norman, Thorand, Barbara, Wichmann, H.-Erich, Illig, Thomas, Hauner, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661577/
https://ncbi.nlm.nih.gov/pubmed/19074982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1646
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