Structural Insight into the Bifunctional Mechanism of the Glycogen-debranching Enzyme TreX from the Archaeon Sulfolobus solfataricus

TreX is an archaeal glycogen-debranching enzyme that exists in two oligomeric states in solution, as a dimer and tetramer. Unlike its homologs, TreX from Sulfolobus solfataricus shows dual activities for α-1,4-transferase and α-1,6-glucosidase. To understand this bifunctional mechanism, we determine...

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Bibliographische Detailangaben
Hauptverfasser: Woo, Eui-Jeon, Lee, Seungjae, Cha, Hyunju, Park, Jong-Tae, Yoon, Sei-Mee, Song, Hyung-Nam, Park, Kwan-Hwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661413/
https://ncbi.nlm.nih.gov/pubmed/18703518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802560200
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