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α-Isopropylmalate, a Leucine Biosynthesis Intermediate in Yeast, Is Transported by the Mitochondrial Oxalacetate Carrier

In Saccharomyces cerevisiae, α-isopropylmalate (α-IPM), which is produced in mitochondria, must be exported to the cytosol where it is required for leucine biosynthesis. Recombinant and reconstituted mitochondrial oxalacetate carrier (Oac1p) efficiently transported α-IPM in addition to its known sub...

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Detalhes bibliográficos
Main Authors: Marobbio, Carlo M. T., Giannuzzi, Giulia, Paradies, Eleonora, Pierri, Ciro L., Palmieri, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661403/
https://ncbi.nlm.nih.gov/pubmed/18682385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804637200
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