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α-Isopropylmalate, a Leucine Biosynthesis Intermediate in Yeast, Is Transported by the Mitochondrial Oxalacetate Carrier
In Saccharomyces cerevisiae, α-isopropylmalate (α-IPM), which is produced in mitochondria, must be exported to the cytosol where it is required for leucine biosynthesis. Recombinant and reconstituted mitochondrial oxalacetate carrier (Oac1p) efficiently transported α-IPM in addition to its known sub...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661403/ https://ncbi.nlm.nih.gov/pubmed/18682385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804637200 |
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