Laminin Isoforms Containing the γ3 Chain Are Unable to Bind to Integrins due to the Absence of the Glutamic Acid Residue Conserved in the C-terminal Regions of the γ1 and γ2 Chains

Laminins are the major cell adhesive proteins in basement membranes, and consist of three subunits termed α, β, and γ. Recently, we found that the Glu residue at the third position from the C termini of the γ1 and γ2 chains is critically involved in integrin binding by laminins. However, the γ3 chai...

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Auteurs principaux: Ido, Hiroyuki, Ito, Shunsuke, Taniguchi, Yukimasa, Hayashi, Maria, Sato-Nishiuchi, Ryoko, Sanzen, Noriko, Hayashi, Yoshitaka, Futaki, Sugiko, Sekiguchi, Kiyotoshi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Glycobiology and Extracellular Matrices
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661386/
https://ncbi.nlm.nih.gov/pubmed/18697739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803553200
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