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Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

Receptor-like roles for ephrin-B proteins are implicated to control axon pathfinding by repulsion, although it is largely unknown how the reverse signals are coupled to downstream intracellular molecules and induce cytoskeletal reorganization at the axon terminal. Here, we show ephrin-B3 (EB3) funct...

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Библиографические подробности
Главные авторы: Xu, Nan-Jie, Henkemeyer, Mark
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661084/
https://ncbi.nlm.nih.gov/pubmed/19182796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2254
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