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Randomized crossover pharmacokinetic study of solvent-based paclitaxel and nab-paclitaxel

PURPOSE: Abraxane (ABI-007) is a 130 nm albumin-bound (nab™) particle formulation of paclitaxel, devoid of any additional excipients. We hypothesized that this change in formulation alters the systemic disposition of paclitaxel compared with conventional solvent-based formulations (sb-paclitaxel, Ta...

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Detalhes bibliográficos
Main Authors: Gardner, Erin R., Dahut, William L., Scripture, Charity D., Jones, Jacquin, Aragon-Ching, Jeanny B., Desai, Neil, Hawkins, Michael J., Sparreboom, Alex, Figg, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661025/
https://ncbi.nlm.nih.gov/pubmed/18594000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4592
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