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The Mycobacterium tuberculosis Phagosome Is a HLA-I Processing Competent Organelle
Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-γ release by CD8(+) T cell clones, we examined the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661020/ https://ncbi.nlm.nih.gov/pubmed/19360129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000374 |
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