Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour

BACKGROUND: Aberrant DNA methylation of CpG islands of cancer-related genes is among the earliest and most frequent alterations in cancerogenesis and might be of value for either diagnosing cancer or evaluating recurrent disease. This mechanism usually leads to inactivation of tumour-suppressor gene...

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Main Authors: Piepoli, Ada, Cotugno, Rosa, Merla, Giuseppe, Gentile, Annamaria, Augello, Bartolomeo, Quitadamo, Michele, Merla, Antonio, Panza, Anna, Carella, Massimo, Maglietta, Rosalia, D'Addabbo, Annarita, Ancona, Nicola, Fusilli, Saverio, Perri, Francesco, Andriulli, Angelo
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660908/
https://ncbi.nlm.nih.gov/pubmed/19257893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-11
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