Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour

BACKGROUND: Aberrant DNA methylation of CpG islands of cancer-related genes is among the earliest and most frequent alterations in cancerogenesis and might be of value for either diagnosing cancer or evaluating recurrent disease. This mechanism usually leads to inactivation of tumour-suppressor gene...

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Main Authors: Piepoli, Ada, Cotugno, Rosa, Merla, Giuseppe, Gentile, Annamaria, Augello, Bartolomeo, Quitadamo, Michele, Merla, Antonio, Panza, Anna, Carella, Massimo, Maglietta, Rosalia, D'Addabbo, Annarita, Ancona, Nicola, Fusilli, Saverio, Perri, Francesco, Andriulli, Angelo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660908/
https://ncbi.nlm.nih.gov/pubmed/19257893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-11
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