Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination

Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, selectively binds distinct chemical patterns, including carbohydrates expressed on Group B streptococcus (GBS). MBL interacts with IgM, resulting in the activation of MBL-associated serine proteases (MASPs), thus is initiati...

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Detalhes bibliográficos
Main Authors: Guttormsen, Hilde-Kari, Stuart, Lynda, Shi, Lei, Carroll, Mike C., Chen, Jianzhu, Kasper, Dennis L., Ezekowitz, R. Alan B., Takahashi, Kazue
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660855/
https://ncbi.nlm.nih.gov/pubmed/18996748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.09.012
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