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Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion

The CDC25 protein phosphatases (CDC25A, B, and C) drive cell cycle transitions by activating key components of the cell cycle engine. CDC25A and CDC25B are frequently overproduced in human cancers. Disruption of Cdc25B or Cdc25C individually or in combination has no effect on mouse viability. Here w...

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Библиографические подробности
Главные авторы: Lee, Gwanghee, White, Lynn S., Hurov, Kristen E., Stappenbeck, Thaddeus S., Piwnica-Worms, Helen
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660721/
https://ncbi.nlm.nih.gov/pubmed/19273838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900751106
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