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Specific molecular recognition of mixed nucleic acid sequences: An aromatic dication that binds in the DNA minor groove as a dimer

Phenylamidine cationic groups linked by a furan ring (furamidine) and related compounds bind as monomers to AT sequences of DNA. An unsymmetric derivative (DB293) with one of the phenyl rings of furamidine replaced with a benzimidazole has been found by quantitative footprinting analyses to bind to...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wang, Lei, Bailly, Christian, Kumar, Arvind, Ding, Daoyuan, Bajic, Miroslav, Boykin, David W., Wilson, W. David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.1.12
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