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Genetic Enhancement of Thalamocortical Network Activity by Elevating α1G-Mediated Low-Voltage-Activated Calcium Current Induces Pure Absence Epilepsy

Absence seizures are a leading form of childhood epilepsy. Human and mouse P/Q-type calcium channel gene mutations initiate a complex absence epilepsy and ataxia phenotype, and in mice, secondarily elevate neuronal low-voltage-activated T-type calcium currents. These currents influence thalamocortic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ernst, Wayne L., Zhang, Yi, Yoo, Jong W., Ernst, Sara J., Noebels, Jeffrey L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660673/
https://ncbi.nlm.nih.gov/pubmed/19211869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2081-08.2009
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