Chargement en cours...
GDNF hyperalgesia is mediated by PLCγ, MAPK/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican
The function of the isolectin B4 (IB4(+))-binding and GDNF-dependent Ret (Ret(+))-expressing non-peptidergic subpopulation of nociceptors remain poorly understood. We demonstrate that acute administration of GDNF sensitizes nociceptors and produces mechanical hyperalgesia in the rat. Intrathecal IB4...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660608/ https://ncbi.nlm.nih.gov/pubmed/18616564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06308.x |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|