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Synthesis of N-linked glycopeptides on solid support and their evaluation as protease substrates

A range of glycopeptides containing protease cleavage sites were synthesized on solid support using Fmoc-based solid phase glycopeptide synthesis. The immobilized peptides were studied as substrates for the proteases chymotrypsin and thermolysin. For chymotrypsin, N-glycosylation of an Asn residue a...

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Detalhes bibliográficos
Main Authors: Bejugam, Mallesham, Maltman, Beatrice A., Flitsch, Sabine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660578/
https://ncbi.nlm.nih.gov/pubmed/19325930
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