Conservation of Carbohydrate Binding Interfaces — Evidence of Human HBGA Selection in Norovirus Evolution

BACKGROUND: Human noroviruses are the major viral pathogens of epidemic acute gastroenteritis. These genetically diverse viruses comprise two major genogroups (GI and GII) and approximately 30 genotypes. Noroviruses recognize human histo-blood group antigens (HBGAs) in a diverse, strain-specific man...

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Main Authors: Tan, Ming, Xia, Ming, Chen, Yutao, Bu, Weiming, Hegde, Rashmi S., Meller, Jarek, Li, Xuemei, Jiang, Xi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660415/
https://ncbi.nlm.nih.gov/pubmed/19337380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005058
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