Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells

Inflammatory brain disease may damage cerebral vascular endothelium leading to cerebral blood flow dysregulation. The proinflammatory cytokine TNF-α causes oxidative stress and apoptosis in cerebral microvascular endothelial cells (CMVEC) from newborn pigs. We investigated contribution of major cell...

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Autores principales: Basuroy, Shyamali, Bhattacharya, Sujoy, Leffler, Charles W., Parfenova, Helena
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
Materias:
Vascular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660262/
https://ncbi.nlm.nih.gov/pubmed/19118162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00381.2008
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