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Suppressed hindlimb perfusion in Rac2(−/−) and Nox2(−/−) mice does not result from impaired collateral growth

While tissue perfusion and angiogenesis subsequent to acute femoral artery occlusion are suppressed in NADPH oxidase 2 (Nox2)-null (Nox2(−/−)) mice, studies have not established the role of Nox2 in collateral artery enlargement. Rac2 is a small GTPase that binds Nox2 and activates Nox2-based NAD(P)H...

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Detalhes bibliográficos
Main Authors: Distasi, Matthew R., Case, Jamie, Ziegler, Matthew A., Dinauer, Mary C., Yoder, Mervin C., Haneline, Laura S., Dalsing, Michael C., Miller, Steven J., Labarrere, Carlos A., Murphy, Michael P., Ingram, David A., Unthank, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660231/
https://ncbi.nlm.nih.gov/pubmed/19151256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00772.2008
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