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Acidosis, Oxygen, and Interference with Mitochondrial Permeability Transition Pore Formation in the Early Minutes of Reperfusion Are Critical to Postconditioning's Success
Repetitive cycles of reflow/reocclusion in the initial 2 min following release of a prolonged coronary occlusion, i.e., ischemic postconditioning (IPoC), salvages ischemic myocardium. We have proposed that the intermittent ischemia prevents formation of mitochondrial permeability transition pores (M...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660166/ https://ncbi.nlm.nih.gov/pubmed/18626679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-008-0737-9 |
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