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Discovery of a sensitive, selective, and tight binding fluorogenic substrate of bovine plasma amine oxidase
We report a novel fluorogenic substrate of bovine plasma amine oxidase (BPAO), namely (2-(6-(aminomethyl)naphthalen-2-yloxy)ethyl)trimethylammonium (ANETA), which displays extremely tight binding to BPAO (K(m) 183±14 nM), and yet is metabolized fairly quickly (k(cat) 0.690±0.010 s(−1)), with the ald...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659760/ https://ncbi.nlm.nih.gov/pubmed/19053593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo8018945 |
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