Production and characterization of monoclonal antibodies to toxic shock syndrome toxin 1 and use of a monoclonal antibody in a rapid, one-step enzyme-linked immunosorbent assay for detection of picogram quantities of toxic shock syndrome toxin 1.

Twenty-six hybridoma cell lines that produced monoclonal antibodies to toxic shock syndrome toxin 1 (TSST-1) were generated by immunizing mice with a highly purified preparation of TSST-1 and fusing their splenic lymphocytes with SP2/0-Ag-14 cells. One monoclonal antibody of the immunoglobulin G1 is...

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Publicado en:	J Clin Microbiol
Autores principales:	Wells, D E, Reeves, M W, McKinney, R M, Graves, L M, Olsvik, O, Bergan, T, Feeley, J C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC265972/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3106406/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.25.3.516-521.1987
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