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Fungicidal activity of amiodarone is tightly coupled to calcium influx
The antiarrhythmic drug amiodarone has microbicidal activity against fungi, bacteria and protozoa. In Saccharomyces cerevisiae, amiodarone triggers an immediate burst of cytosolic Ca(2+), followed by cell death markers. Ca(2+) transients are a common response to many forms of environmental insults a...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659656/ https://ncbi.nlm.nih.gov/pubmed/18294196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1567-1364.2008.00354.x |
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