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Design, Synthesis and Biological Evaluation of a Radiolabelled Antagonist-Bombesin Analog as Targeting Vector
The gastrin releasing peptide receptor (GRP-R) is over-expressed on a number of tumors and cancer cell lines including pancreas, prostate, breast, gastrointestinal and small cell lung cancer (SCLC). Radiolabeled bombesin (BBN) analogues have exhibited high binding affinity and specificity to the GRP...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659627/ https://ncbi.nlm.nih.gov/pubmed/18808168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800290c |
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