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Design, Synthesis and Biological Evaluation of a Radiolabelled Antagonist-Bombesin Analog as Targeting Vector

The gastrin releasing peptide receptor (GRP-R) is over-expressed on a number of tumors and cancer cell lines including pancreas, prostate, breast, gastrointestinal and small cell lung cancer (SCLC). Radiolabeled bombesin (BBN) analogues have exhibited high binding affinity and specificity to the GRP...

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Bibliographic Details
Main Authors: Wael, Abd-Elgaliel, Fabio, Gallazzi, Jered, Garrison, Tammy, Rold, Gary, Sieckman, Said, Daibes Figueroa, Timothy, Hoffman, Susan, Lever
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659627/
https://ncbi.nlm.nih.gov/pubmed/18808168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800290c
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