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PGE(2) And Its Cognate EP Receptors Control Human Adult Articular Cartilage Homeostasis and Are Linked to the Pathophysiology of Osteoarthritis

OBJECTIVE: To elucidate the pathophysiologic links between prostaglandin E(2) (PGE(2)) and osteoarthritis by characterizing the catabolic effects of PGE(2) and its unique receptors in human adult articular chondrocytes. METHODS: Human adult articular chondrocytes were cultured in monolayer or algina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Xin, Ellman, Michael, Muddasani, Prasuna, Wang, James H-C, Cs-Szabo, Gabriella, van Wijnen, Andre J, Im, Hee-Jeong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659545/
https://ncbi.nlm.nih.gov/pubmed/19180509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24258
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