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A High-Speed Congenic Strategy Using First-Wave Male Germ Cells

BACKGROUND: In laboratory mice and rats, congenic breeding is essential for analyzing the genes of interest on specific genetic backgrounds and for analyzing quantitative trait loci. However, in theory it takes about 3–4 years to achieve a strain carrying about 99% of the recipient genome at the ten...

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書誌詳細
主要な著者: Ogonuki, Narumi, Inoue, Kimiko, Hirose, Michiko, Miura, Ikuo, Mochida, Keiji, Sato, Takahiro, Mise, Nathan, Mekada, Kazuyuki, Yoshiki, Atsushi, Abe, Kuniya, Kurihara, Hiroki, Wakana, Shigeharu, Ogura, Atsuo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659429/
https://ncbi.nlm.nih.gov/pubmed/19333383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004943
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