A High-Speed Congenic Strategy Using First-Wave Male Germ Cells

BACKGROUND: In laboratory mice and rats, congenic breeding is essential for analyzing the genes of interest on specific genetic backgrounds and for analyzing quantitative trait loci. However, in theory it takes about 3–4 years to achieve a strain carrying about 99% of the recipient genome at the ten...

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Detalhes bibliográficos
Main Authors: Ogonuki, Narumi, Inoue, Kimiko, Hirose, Michiko, Miura, Ikuo, Mochida, Keiji, Sato, Takahiro, Mise, Nathan, Mekada, Kazuyuki, Yoshiki, Atsushi, Abe, Kuniya, Kurihara, Hiroki, Wakana, Shigeharu, Ogura, Atsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659429/
https://ncbi.nlm.nih.gov/pubmed/19333383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004943
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