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Structure of a RSC–nucleosome complex and insights into chromatin remodeling

ATP-dependent chromatin-remodeling complexes, such as RSC, can reposition, evict or restructure nucleosomes. A structure of a RSC–nucleosome complex with a nucleosome determined by cryo-EM shows the nucleosome bound in a central RSC cavity. Extensive interaction of RSC with histones and DNA seems to...

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Autors principals: Chaban, Yuriy, Ezeokonkwo, Chukwudi, Chung, Wen-Hsiang, Zhang, Fan, Kornberg, Roger D, Maier-Davis, Barbara, Lorch, Yahli, Asturias, Francisco J
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659406/
https://ncbi.nlm.nih.gov/pubmed/19029894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1524
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