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Cyclophosphamide-Induced Bladder Inflammation Sensitizes and Enhances P2X Receptor Function in Rat Bladder Sensory Neurons

We studied sensitization of retrogradely labeled bladder sensory neurons and plasticity of P2X receptor function in a model of cystitis using patch-clamp techniques. Saline (control) or cyclophosphamide (CYP) was given intraperitoneally to rats on days 0, 2, and 4. On day 5, lumbosacral (LS, L6–S2)...

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Detalhes bibliográficos
Main Authors: Dang, Khoa, Lamb, Kenneth, Cohen, Michael, Bielefeldt, Klaus, Gebhart, G. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659400/
https://ncbi.nlm.nih.gov/pubmed/17959738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00211.2007
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