Identification of a chemical probe for NAADP by virtual screening

Research into the biological role of the Ca(2+)-releasing second messenger NAADP (nicotinic acid adenine dinucleotide phosphate) has been hampered by a lack of chemical probes. To find new chemical probes for exploring NAADP signaling, we turned to virtual screening, which can evaluate millions of m...

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Main Authors: Naylor, Edmund, Arredouani, Abdelilah, Vasudevan, Sridhar R., Lewis, Alexander M., Parkesh, Raman, Mizote, Akiko, Rosen, Daniel, Thomas, Justyn M., Izumi, Minoru, Ganesan, A., Galione, Antony, Churchill, Grant C.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659327/
https://ncbi.nlm.nih.gov/pubmed/19234453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.150
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