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Hyperphagia and Obesity in Female Mice Lacking Tissue Inhibitor of Metalloproteinase-1

Certain matrix metalloproteinases and their regulators, the tissue inhibitors of metalloproteinases (TIMPs), are involved in development and remodeling of adipose tissue. In studying Timp1(<tm1Pds>) mice, which have a null mutation in Timp1 (Timp1(−/−)), we observed that females exhibit increa...

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Detalhes bibliográficos
Main Authors: Gerin, Isabelle, Louis, Gwendolyn W., Zhang, Xuan, Prestwich, Tyler C., Kumar, T. Rajendra, Myers, Martin G., MacDougald, Ormond A., Nothnick, Warren B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659269/
https://ncbi.nlm.nih.gov/pubmed/19036876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1409
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