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The Carboxyl-terminal Domain of RNA Polymerase II Is Not Sufficient to Enhance the Efficiency of Pre-mRNA Capping or Splicing in the Context of a Different Polymerase

Eukaryotic messenger RNA precursors (pre-mRNAs) synthesized by RNA polymerase II (RNAP II) are processed co-transcriptionally. The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II is thought to mediate the coupling of transcription with pre-mRNA processing by coordinating t...

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Bibliografiske detaljer
Main Authors: Natalizio, Barbara J., Robson-Dixon, Nicole D., Garcia-Blanco, Mariano A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659228/
https://ncbi.nlm.nih.gov/pubmed/19176527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806919200
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