Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice

AIM: To investigate the pathogenic role of cathepsin B and the protective effect of a cathepsin B inhibitor (CA-074Me) in fulminant hepatic failure in mice. METHODS: LPS/D-Gal N was injected into mice of the model group to induce fulminant hepatic failure; the protected group was administered CA-074...

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Bibliographic Details
Main Authors: Yan, Bing-Zhu, Wang, Wei, Chen, Li-Yan, Bi, Man-Ru, Lu, Yan-Jie, Li, Bao-Xin, Yang, Bao-Shan
Format: Artigo
Language:Inglês
Published: The WJG Press and Baishideng 2009
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658851/
https://ncbi.nlm.nih.gov/pubmed/19291823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.1231
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