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The Added Value of Concurrently-Administered Temozolomide Versus Adjuvant Temozolomide Alone in Newly-Diagnosed Glioblastoma

PURPOSE: Temozolomide (TMZ), given concurrently with radiotherapy (RT) and as adjuvant monotherapy afterwards, has led to improved survival in glioblastoma multiforme (GBM). However, it is unclear whether its primary mechanism of action is through enhancement of radiation response or through indepen...

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Detalhes bibliográficos
Main Authors: Sher, David J., Henson, John, Avutu, Bindu, Hochberg, Fred, Batchelor, Tracy, Martuza, Robert, Barker, Fred, Loeffler, Jay S., Chakravarti, Arnab
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658810/
https://ncbi.nlm.nih.gov/pubmed/18231723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9530-8
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