The Added Value of Concurrently-Administered Temozolomide Versus Adjuvant Temozolomide Alone in Newly-Diagnosed Glioblastoma

PURPOSE: Temozolomide (TMZ), given concurrently with radiotherapy (RT) and as adjuvant monotherapy afterwards, has led to improved survival in glioblastoma multiforme (GBM). However, it is unclear whether its primary mechanism of action is through enhancement of radiation response or through indepen...

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Autori principali: Sher, David J., Henson, John, Avutu, Bindu, Hochberg, Fred, Batchelor, Tracy, Martuza, Robert, Barker, Fred, Loeffler, Jay S., Chakravarti, Arnab
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658810/
https://ncbi.nlm.nih.gov/pubmed/18231723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9530-8
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