The Added Value of Concurrently-Administered Temozolomide Versus Adjuvant Temozolomide Alone in Newly-Diagnosed Glioblastoma

PURPOSE: Temozolomide (TMZ), given concurrently with radiotherapy (RT) and as adjuvant monotherapy afterwards, has led to improved survival in glioblastoma multiforme (GBM). However, it is unclear whether its primary mechanism of action is through enhancement of radiation response or through indepen...

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Main Authors: Sher, David J., Henson, John, Avutu, Bindu, Hochberg, Fred, Batchelor, Tracy, Martuza, Robert, Barker, Fred, Loeffler, Jay S., Chakravarti, Arnab
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658810/
https://ncbi.nlm.nih.gov/pubmed/18231723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9530-8
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