Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever. Amapari (AMAV) and Tacaribe (TCRV), two nonpathogenic NW clade B arenaviruses that do not use human TfR1, are closely related t...

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Detalhes bibliográficos
Main Authors: Abraham, Jonathan, Kwong, Jo Ann, Albariño, César G., Lu, Jiajie G., Radoshitzky, Sheli R., Salazar-Bravo, Jorge, Farzan, Michael, Spiropoulou, Christina F., Choe, Hyeryun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658809/
https://ncbi.nlm.nih.gov/pubmed/19343214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000358
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