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Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome

BACKGROUND: Whole genome sequencing techniques have added a new dimension to studies on bacterial adaptation, evolution and diversity in chronic infections. By using this powerful approach it was demonstrated that Pseudomonas aeruginosa undergoes intense genetic adaptation processes, crucial in the...

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Bibliografiske detaljer
Main Authors: Dötsch, Andreas, Pommerenke, Claudia, Bredenbruch, Florian, Geffers, Robert, Häussler, Susanne
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658670/
https://ncbi.nlm.nih.gov/pubmed/19152677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-29
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