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Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment

Tuberous sclerosis complex (TSC) is a relatively rare autosomal dominant disorder characterized by widespread benign tumor formation in a variety of organs. Mutations in either TSC1 or TSC2 tumor suppressor gene are responsible for TSC. The gene products of TSC1 and TSC2, also known as hamartin and...

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Detalhes bibliográficos
Main Authors: Inoki, Ken, Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657945/
https://ncbi.nlm.nih.gov/pubmed/19297407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp032
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