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Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment

Tuberous sclerosis complex (TSC) is a relatively rare autosomal dominant disorder characterized by widespread benign tumor formation in a variety of organs. Mutations in either TSC1 or TSC2 tumor suppressor gene are responsible for TSC. The gene products of TSC1 and TSC2, also known as hamartin and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Inoki, Ken, Guan, Kun-Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657945/
https://ncbi.nlm.nih.gov/pubmed/19297407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp032
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