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Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment
Tuberous sclerosis complex (TSC) is a relatively rare autosomal dominant disorder characterized by widespread benign tumor formation in a variety of organs. Mutations in either TSC1 or TSC2 tumor suppressor gene are responsible for TSC. The gene products of TSC1 and TSC2, also known as hamartin and...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657945/ https://ncbi.nlm.nih.gov/pubmed/19297407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp032 |
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