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Targeting Pro-Invasive Oncogenes with Short Chain Fatty Acid-Hexosamine Analogs Inhibits the Mobility of Metastatic MDA-MB-231 Breast Cancer Cells

Per-butanoylated N-acetyl-d-mannosamine (Bu(4)ManNAc), a SCFA-hexosamine cancer drug candidate with activity manifest through intact n-butyrate-carbohydrate linkages, reduced the invasion of metastatic MDA-MB-231 breast cancer cells unlike per-butanoylated-d-mannose (Bu(5)Man), a clinically-tested c...

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Detalhes bibliográficos
Main Authors: Campbell, Christopher T., Aich, Udayanath, Weier, Christopher A., Wang, Jean J., Choi, Sean S., Wen, Mary M., Maisel, Katharina, Sampathkumar, Srinivasa-Gopalan, Yarema, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657678/
https://ncbi.nlm.nih.gov/pubmed/19053749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800873k
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