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Targeting Pro-Invasive Oncogenes with Short Chain Fatty Acid-Hexosamine Analogs Inhibits the Mobility of Metastatic MDA-MB-231 Breast Cancer Cells
Per-butanoylated N-acetyl-d-mannosamine (Bu(4)ManNAc), a SCFA-hexosamine cancer drug candidate with activity manifest through intact n-butyrate-carbohydrate linkages, reduced the invasion of metastatic MDA-MB-231 breast cancer cells unlike per-butanoylated-d-mannose (Bu(5)Man), a clinically-tested c...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657678/ https://ncbi.nlm.nih.gov/pubmed/19053749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800873k |
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