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Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome

Mono-ADP-ribosylation is a reversible posttranslational modification that modulates the function of target proteins. The enzymes that catalyze this reaction in mammalian cells are either bacterial pathogenic toxins or endogenous cellular ADP-ribosyltransferases. For the latter, both the enzymes and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dani, Nadia, Stilla, Annalisa, Marchegiani, Adriano, Tamburro, Antonio, Till, Susanne, Ladurner, Andreas G., Corda, Daniela, Di Girolamo, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657436/
https://ncbi.nlm.nih.gov/pubmed/19246377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900066106
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