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Double Dissociation of the Effects of Medial and Orbital Prefrontal Cortical Lesions on Attentional and Affective Shifts in Mice

Many neuropsychiatric diseases are associated with cognitive rigidity linked to prefrontal dysfunction. For example, schizophrenia and Parkinson's disease are associated with performance deficits on the Wisconsin Card Sorting Test, which evaluates attentional set shifting. Although the genetic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bissonette, Gregory B., Martins, Gabriela J., Franz, Theresa M., Harper, Elizabeth S., Schoenbaum, Geoffrey, Powell, Elizabeth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657142/
https://ncbi.nlm.nih.gov/pubmed/18971455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2820-08.2008
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