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Double Dissociation of the Effects of Medial and Orbital Prefrontal Cortical Lesions on Attentional and Affective Shifts in Mice

Many neuropsychiatric diseases are associated with cognitive rigidity linked to prefrontal dysfunction. For example, schizophrenia and Parkinson's disease are associated with performance deficits on the Wisconsin Card Sorting Test, which evaluates attentional set shifting. Although the genetic...

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Autors principals: Bissonette, Gregory B., Martins, Gabriela J., Franz, Theresa M., Harper, Elizabeth S., Schoenbaum, Geoffrey, Powell, Elizabeth M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657142/
https://ncbi.nlm.nih.gov/pubmed/18971455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2820-08.2008
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