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Lipid bilayer curvature and pore formation induced by charged linear polymers and dendrimers: the effect of molecular shape

We performed molecular dynamics (MD) simulations of multiple copies of poly-L-lysine (PLL) and charged polyamidoamine (PAMAM) dendrimers in dimyristoylphosphatidylcholine (DMPC) bilayers with explicit water using the coarse-grained model developed by Marrink et al. (J. Chem. Theory and Comput. 2008,...

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Bibliografske podrobnosti
Main Authors: Lee, Hwankyu, Larson, Ronald G.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657094/
https://ncbi.nlm.nih.gov/pubmed/18767788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp805026m
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