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The Epstein–Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim

Current knowledge suggests that the balance between life and death within a cell can be controlled by the stable engagement of Bcl-2-related proapoptotic proteins such as Bak, Bax, and Bim by survival proteins such as Bcl-2. BHRF1 is a prosurvival molecule from Epstein–Barr virus that has a high deg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Desbien, Anthony L., Kappler, John W., Marrack, Philippa
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657086/
https://ncbi.nlm.nih.gov/pubmed/19293378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901036106
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