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A TNF region haplotype offers protection from typhoid fever in Vietnamese patients

The genomic region surrounding the TNF locus on human chromosome 6 has previously been associated with typhoid fever in Vietnam. We used a haplotypic approach to understand this association further. Eighty single nucleotide polymorphisms (SNPs) spanning a 150 kb region were genotyped in 95 Vietnames...

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Détails bibliographiques
Auteurs principaux: Dunstan, Sarah J., Hue, Nguyen Thi, Rockett, Kirk, Forton, Julian, Morris, Andrew P., Diakite, Mahamadou, Lanh, Mai Ngoc, Phuong, Le Thi, House, Deborah, Parry, Christopher M., Vinh, Ha, Hieu, Nguyen T., Dougan, Gordon, Hien, Tran Tinh, Kwiatowski, Dominic, Farrar, Jeremy J.
Format: Artigo
Langue:Inglês
Publié: 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656995/
https://ncbi.nlm.nih.gov/pubmed/17503085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-007-0372-9
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