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Deoxycholate promotes survival of breast cancer cells by reducing the level of pro-apoptotic ceramide
INTRODUCTION: At physiologic concentration in serum, the bile acid sodium deoxycholate (DC) induces survival and migration of breast cancer cells. Here we provide evidence of a novel mechanism by which DC reduces apoptosis that is induced by the sphingolipid ceramide in breast cancer cells. METHODS:...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656903/ https://ncbi.nlm.nih.gov/pubmed/19087284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2211 |
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