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TANK-binding kinase-1 plays an important role during in vitro and in vivo type I interferon responses to DNA virus infections
TANK-binding kinase-1 (TBK1) and the inducible IκB kinase (IKK-i) have recently been shown to activate type I interferon (IFN) responses elicited by intracellular detection of RNA or DNA from infecting viruses. Detection of viral RNA is mediated by RIG-I or Mda5 pathways in which TBK1 and IKK-i have...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656676/ https://ncbi.nlm.nih.gov/pubmed/19201879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802466 |
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